PEA

What is palmitoylethanolamide (PEA)?

PEA (palmitoylethanolamide) is an endogenous fatty acid which has a positive effect on a number of cellular receptors. It helps deal with pain, inflammation and immune system disorders and it is completely safe in any amounts.

PEA has been tested through more than 400 different medical studies each of which confirmed its unprecedented combination of efficiency and safety. It was also a matter of interest of Nobel laureate Rita Levi-Montalcini, as well as numerous other scientists. Recently, after major advancements in production methods, palmitoylethanolamide regained momentum and numerous scientists are conducting studies regarding its effects as well as safety. Medical journals hold many recent examples of PEA-related research.

PEA is created inside the body naturally and used to trigger a number of biological functions that deal with pain and inflammation management. Its effects are spread both within and outside the endocannabinoid system.

It also helps other endogenous molecules such as anandamide present their benefits by jointly overwhelming the enzymes that destroy them both.

Another major benefit of palmitoylethanolamide is that it can be used together with any drug or supplement without any side effects. This makes it an incredibly important solution to chronic pain issues and gradually and safely getting off painkillers and opioids without any need to endure pain in the process.

What does PEA affect?

PEA affects a number of nuclear receptors, including PPAR-alpha, GPR55, GPR119, CB1, CB2 and TRPV-1. In total, these are responsible for proper operation of kidneys, skeletal muscle, intestines, adrenal gland, heart, central and peripheral nervous systems, liver, lungs, hematopoietic cells, B cells, macrophages, blood cells, bone cells, cerebellum, jejunum, ileum, pancreas, GI tract and more.

Aside from pain and inflammation, the effects described above make it clear why PEA  is an important part of proper functioning of the immune system and very efficient against a number of autoimmune diseases and their symptoms.

Palmitoylethanolamide also promotes ketogenesis, regulates the feeling of hunger and secretion of incretin and insulin and controls iNOX and COX-2 expression and influx of neutrophils.

Safety of PEA

In short, PEA holds several major safety benefits:

• There is no way to overdose on PEA
• There are no side-effects
• There is no habituation – the more you take, the more efficient it is
• There are no negative interactions with drugs
• There is no addiction to PEA
• There are no allergic reactions

All this is possible because PEA is an endogenous fatty acid amide – created inside the body and easily broken down by enzymes. It is a part of many organisms, including plants, animals and even single cell organisms. Our bodies are inherently used to PEA and all of the drugs need to work with or around it. It is literally a part of our internal systems, just often insufficient when it comes to amounts.

Our EndoPEA and Liposomal EndoPEA solve this issue with ease. Order liposomal palmitoylethanolamide and experience the benefits first-hand.